Skin and Allergy News Digital Network | Calcineurin Inhibitors Are Steroid Sparing in Chronic Hand Dermatitis Skin and Allergy News Digital Network WAIKOLOA, HAWAII – The calcineurin inhibitors are effective for long-term maintenance therapy in chronic hand dermatitis, despite their black box warning, and can help reduce the use of topical steroids, according to dermatologist Joseph F. Fowler Jr. |