Anthracycline, Trastuzumab for Breast CA Up Heart Failure Risk Doctors Lounge For women with incident, invasive breast cancer, treatment with anthracycline and trastuzumab is associated with an increased risk of heart failure and/or cardiomyopathy, compared to having no chemotherapy, according to a study published in the Sept. Study: Trastuzumab (Herceptin) Raises Risk of Heart Failure |