MedPage Today | FDA Approves Everolimus for Liver Rejection MedPage Today Despite the similarity in generic names, everolimus and tacrolimus are in different drug classes. Whereas everolimus is an mTOR inhibitor (similar to sirolimus, also known as rapamycin and sold as Rapamune), tacrolimus is a calcineurin inhibitor. Novartis' Zortress cleared by FDA for liver transplants Novartis drug Zortress is first in over a decade approved by FDA to prevent ... FDA approves Zortress to prevent liver transplant rejection |