Mixed Results For Spironolactone In Heart Failure With Preserved Ejection ... Forbes Although the mineralocorticoid receptor antagonists (MRAs) spironolactone and eplerenone (Inspra, Pfizer) have been shown to be beneficial in patients with heart failure (HF) with reduced ejection fraction (EF), their role in heart failure patients ... Heart Failure Drug May Not Ease Symptoms in Some Long-Term Use of Medication Does Not Improve Symptoms for Heart Failure ... Spironolactone disappoints in preserved-EF heart failure: Aldo-DHF in print |