Medscape | Early Menopause May Increase Heart Failure Risk Medscape Early natural menopause is significantly associated with heart failure (HF) when compared with menopause at age 50 to 54 years. The increase in risk is even more pronounced in women who smoke. Iffat Rahman, PhD, from the Institute of Environmental ... Early menopause may up heart failure risk Early Menopause Increases Heart Failure Risk In Smokers Premature Menopause can Lead to Heart Failure |