Rituximab joint protective benefits capped – from News-Medical.NetNews-Medical.netAs reported in Rheumatology, the researchers found that the likelihood for radiographic evidence of progressive RA structural damage to the hands and feet at 1 year was n…
Biogen v. Glaxosmithkline: Prosecution History Disclaimer and Claim ConstructionPatently-ORituximab binds to this epitope. After Biogen filed its application, other scientists discovered that the CD20 antigen had a second small loop (originally thought…
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Federal Circuit Finds Prosecution History Disclaimer In Enablement Arguments
Mondaq News Alerts (registration) The specification describes Biogen’s product Rituxan® (rituximab) as a preferred embodiment. Rituximab binds to a large loop of the CD20 protein that is exposed on the cell surface. This loop constitutes the particular “epitope” recognized by the … |
OncLiveDutch Researcher Focuses on Fc Signaling in Targeting CD20 – OncLiveOncLiveBuilding on the success achieved with rituximab (RTX), other anti-CD20 monoclonal antibodies (mAbs) are being investigated. The fully human anti-CD20 mAb ofatumumab was a…
MedscapeChoice of First-Line Therapy in Follicular Lymphoma Debated – MedscapeMedscapeThe editorial was prompted by the publication of results from a large Italian phase 3 trial, known as FOLL05, which compared 3 chemotherapy regimens: R-CHOP (rituxima…
 OncLive |
Targeting CD20: Rituximab’s Success Fuels Interest in New Agents – OncLive
OncLive The first anticancer antibody on the market was rituximab, which targets the membrane protein CD20 and, since its approval in the late 1990s, it has revolutionized the treatment of B-cell malignancies, with huge improvements in survival rates. However … |
 Bioscience Technology |
MCCIR scientists use video imaging to investigate effectiveness of rituximab …
News-Medical.net Professor Daniel Davis and his team used high quality video imaging to investigate why the drug rituximab is so effective at killing cancerous B cells. It is widely used in the treatment of B cell malignancies, such as lymphoma and leukaemia – as well … ‘Achilles’ heel’ of cancer cells discovery by Manchester scientists could …Mancunian Matters |
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Video reveals cancer cells’ Achilles’ heel
HealthCanal.com Professor Daniel Davis and his team used high quality video imaging to investigate why the drug rituximab is so effective at killing cancerous B cells. It is widely used in the treatment of B cell malignancies, such as lymphoma and leukaemia – as well … |
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Video reveals cancer cells’ Achilles’ heel – EurekAlert!
EurekAlert (press release) Professor Daniel Davis and his team used high quality video imaging to investigate why the drug rituximab is so effective at killing cancerous B cells. It is widely used in the treatment of B cell malignancies, such as lymphoma and leukaemia – as well … |
Smoking Raises Risk of Lung Disease in RA – MedPage TodayMedPage TodayThese changes are likely to reflect the earlier use of older immunosuppressive agents such as cyclophosphamide and the wider use of newer agents such as mycophenolate mofetil (CellCe…