Materials Views (blog)Curing diabetes, with a little help from polymer science: coating could make …Materials Views (blog)Despite the significant potential of this treatment, its clinical application is limited due to islet instability during isolati…
Existing drugs boost new cancer vax responsesFierceVaccinesResearchers at the University of Pennsylvania are looking at using daclizumab (Zenapax)–a monoclonal antibody used to prevent transplant rejection–to target the Tregs and convert them into no…
Rigel Advances Asthma Programs: Two Inhaled Drug Candidates Take Aim at Acute …Sacramento Bee… R343, an inhaled SYK inhibitor that has completed Phase 1 clinical trials for asthma; R333, a topical JAK/SYK inhibitor for discoid lupus; and R548, an o…
Veloxis Pharmaceuticals announces financial results for the first quarter 2012 …Sacramento BeeThe primary endpoint of the study, a composite endpoint (biopsy proven acute rejection, graft failure, loss to follow up or death), will be evaluated after …
Veloxis Pharmaceuticals announces financial results for the first quarter 2012 …MarketWatch (press release)The primary endpoint of the study, a composite endpoint (biopsy proven acute rejection, graft failure, loss to follow up or death), will be eva…
The NIH Is Going to Discover Drugs… Really?ForbesA JAK inhibitor was hypothesized to be effective in diseases where the immune system is overactive, such as organ transplant rejection, psoriasis, and RA. When a brand new agent has been discovered by …
SunHerald.comSenior with leukemia to walk at graduationSunHerald.comIf he can avoid transplant rejection and attacks on an immune system seriously weakened by the drugs, he can probably get his doctor's permission to accept his diploma with the res…
A Brief History of TofacitinibForbesIn the summer of 1993, Dr. Paul Changelian, a scientist in Pfizer's immune suppression group, was looking for a new way to prevent organ transplant rejection. Paul, always on the lookout for new ideas, particular…
Selecta Biosciences Receives 2012 Edison Award's Gold Medal for Best …MarketWatch (press release)Examples for applications include autoimmune diseases, allergies and transplant rejection. Selecta's pipeline currently contains vaccines for smo…
Eva Markvoort inspires an appNew Westminster News LeaderMarkvoort had a double lung transplant in 2007 that initially gave her physical freedom before transplant rejection set in. She died two years ago at the age of 25 awaiting another transplant. Whe…