Prednisone/MTX Tight Control Best First Step for Early RA Medscape In both groups of the study, if the patient did not reach remission 5 weeks after receiving the maximum tolerable dosage of MTX subcutaneously, cyclosporine was added (later amended to adalimumab). Coauthor Johannes WG Jacobs, PhD, MD, ... Low-Dose Prednisone Inclusion in a Methotrexate-Based, Tight Control Strategy ... |